Students will attend theoretical lectures and practical lessons/seminars that will take place in the Toxicology Section AIT II, as well as the toxicological laboratory.

After completing the course, students are expected to be able to:

• describe the general mechanisms of acute intoxications and types of intoxications;
• know the parameters of acute intoxication, phase I and phase II reactions, receptors and specific interactions with toxicodynamic receptors;
• master notions related to general measures for stabilization in acute intoxication;
• retain notions regarding measures to increase the elimination of toxic substances;
• know specifics about the main antidotes and their mechanisms of action;
• describe the main toxidromes;
• master notions about acute intoxication with psychotropic substances, alcohols and glycols, metals and opioids;
• know the main measures used to monitor and support patients in toxicological intensive therapy;
• make an effort to practice and improve their clinical thinking skills;
• demonstrate their implication in scientific activities, for example by writing an article or participating in studies within this specialty;
• participate in scientific projects that are compatible with european academic guidelines.

After completing the course, students are expected to have the following communication abilities:

 Professional conduct

• to demonstrate a professional attitude towards the patients and their colleagues
• to coordinate the activities of the toxicological intensive therapy unit in close collaboration with the available medical personnel
• to promote and maintain a safe workplace environment, taking into consideration the risk of contamination or injury with the medical equipment and instruments necessary in this specialty
• to understand the importance of continuous medical education and training, allowing them to develop their professional abilities based on current scientific data

Ethical conduct

• to apply the ethical principals related to medical practice
• to respect patients’ rights
• to give priority to treatment options that correspond to the individual needs of the patients
• to respect the patients and their fellow colleagues without discrimination
• to respect juridic, legal and administrative procedures, as well as the rules of conduct for medical practitioners

Goals of the discipline:

General objectives:

• To provide students with the knowledge required to establish the etiopathogenesis and diagnosis of acute intoxications.
• To train students in various aptitudes, behaviors, attitudes and abilities, as well as to impart the values necessary for their medical clinical practice and intensive therapy.
• To promote medical and human ethical values, teach the ethical norms of care for intoxicated patients and the appropriate way to interact with patients and their families.
• To make connections between notions taught in Clinical Toxicology courses and students’ previous medical experiences.
• The evaluation of student performance is based on periodic and final evaluations, testing their level of knowledge and aptitudes.
• Being familiar with the course objectives, in order to assume any related responsibilities.

Specific Objectives:

After completing these courses, students are expected to:

• understand and be able to define the mechanisms of acute intoxication;
• know the clinical and paraclinical aspects of acute intoxications;
• comprehend notions about the therapeutic methods used for acute intoxications;
• retain some notions regarding the methods used in a toxicological analytic laboratory;
• gain some notions related to antidotes and their mechanisms of action.

Student Bibliography:

• 2006 - „Diagnostic si tratament in intoxicatiile acute", autori: Victor A. Voicu, Radu Macovei, Liviu Miclea.
• 2012 editie revizuita si adaugita a „Ghidului de Toxicologie Clinica", editura Brumar Timisoara. Colectivul de autori: Victor A. Voicu, Radu Macovei, Liviu Miclea; colaboratori - Mihail Silviu Tudosie; Bogdan OpriALAL; Mihai IonicAL.