The didactic activity at the Discipline of Pharmaceutical Chemistry takes place during the 3^rd and 4^th study years.

The course aims to the complex presentation of drug substances based on chemical structures, taking into account their pharmacological properties, each active principle being presented in terms of common international name, chemical structure, methods of synthesis, physico-chemical and pharmaco-chemical properties, toxicological, therapeutic indications, pharmaceutical products.

Practical work includes main aspects of synthesis, in which students get acquainted with some basic operations of drug synthesis. They also work to identify and to do the qualitative and quantitative control of some drug substances, acquiring the necessary skills to perform the drug analysis, corresponding to the requirements of the Pharmacopoeia monographs.

Within the discipline are also taught two optional courses: Drugs for veterinary use and Drug Design Strategies, which addresses to students in the 5^th year.

The concern of didactic team are the research and the  thoroughgoing study of some themes studied for many years; the main research directions are the design studies, synthesis and characterization of new derivatives with potential therapeutic action, from the following classes:

• thioureas of 4-substituted phenoxymethylbenzoic acids, 2-phenylethyl benzoic acid, 2-thiophenecarboxylic acid, 3-thiophenecarboxylic acid and 2-thiopheneacetic acid,
• pyrazole compounds,
• tricyclic derivatives with central heptagonal cycle,
• sulfonic derivatives,
• substituted N-(2-dialkylaminoethyl) benzanilide,
• compounds with diarylsulfonamidic structure,
• 1,4- dihydropyridine.

Within these great research themes, students who are working on the student's academic groups are also trained and then they prepare their license work which are always accompanied by a rich experimental part.

Research activity was appreciated over time by awarding prizes, such as "Iuliu Hatieganu" prize of Romanian Academy awarded to Prof. Alexandru Missir and Prof. Ileana Chirita for the work done in the field of drug synthesis. In terms of research activity submitted by young researchers is remarkable the prize awarded by Gedeon Richter to Prof. Carmen Limban, and at the poster section to Prof. Camelia Elena Stecoza (Iasi 1998), and the prize at the e-posters category on the Design of Bioactive Substances section to Assoc. Prof. Diana Nuta (Iasi 2014).

In 2015, Assoc. Prof. Mihai NiALulescu received the Excellence Award for Pharmaceutical Research granted by the National College of Pharmacists. Within the scientific research activity a number of 13 doctoral theses and a habilitation thesis (Prof. Carmen Limban) were finalized at the department. The teaching staff participated in a series of scientific events, symposiums and national and international congresses, and held a sustained activity within the Pharmaceutical Sciences Society of Romania by participating in the scientific committee of Farmacia journal and its Editorial Advisory Board (Prof. Ileana Chirita and Prof. Camelia Elena Stecoza) and as a member of the Editorial Council of Biointerface Research in Applied Chemistry and Letters in Applied NanoBioScience (Prof. Carmen Limban). The teaching staff also works in the Integrated Research-Innovation Center for Organic Synthesis and Analysis, Biological and Pharmacological Evaluation (http://erris.gov.ro).