Disciplina Geriatrie și Gerontologie II - Spitalul Boli Cronice "Sf. Luca"

Prof. univ. Spiru Luiza titular
Șef Lucrări Ioancio Ioana titular
Asist. univ. Constantin Alexandra Oana determinat
Asist. univ. Rasuceanu-Diaconescu Alexandra-Mariela determinat

Incepand cu anul 1997, Departamentul Universitar de Geriatrie şi Gerontologie prin catedra de Geriatrie-Gerontologie a U.M.F. ,,Carol Davila” a cunoscut o dezvoltare acerba, implicandu-se ca si coordonator al proiectului Tempus Phare ROMGER SJEP 12507, finantat de CE in cadrul FP%, pentru:

  1. recunosterea academica a specialitatii de Geriatrie-Gerontologie in Romania si crearea primei Clinici Universitare de profil in cadrul Institutului National de Geriatrie si Gerontologie ,,Ana Aslan”
  2. crearea primului Colegiu Universitar (de scurta durata) de Geriatrie, Gerontologie si Asistenta Sociala Varstnic, U.M.F. ,,Carol Davila”;
  3. crearea Sylabus-ului si Curricula in Geriatrie, Gerontologie si Psihogeriatrie in consortiul european reprezentat de clinicile de geriatrie in Suedia, Franta, Grecia, Spania, Italia si Malta.

Echipele medicale sunt alcatuite din profesionisti in domeniu: medici cu doua sau trei specialitati (medicina interna, geriatrie gerontologie, gerontopsihiatrie, psihiatrie, neurologie, gastroenterologie, medicina fizica si de recuperare, cardiologie, etc) si multiple competente (terapie laser, imagistica, ultrasonografie echo-doppler, etc), psihologi, doctori in cercetare, asistente medicale cu studii universitare, asistente medicale cu specialitate in geriatrie si asistenta sociala a varstnicului, kinetoterapeuti, etc.

Personalul medical este pregatit si instruit prin intermediul cursurilor si orelor de educatie medicala continua, in tara si in strainatate, majoritatea evenimentelor fiind organizate cu sprijinul stiintific al Departamentului Universitar de Geriatrie si Gerontologie, prin afilierea la diverse asociatii profesionale in domeniu. Astfel, pacientii beneficiaza de implementarea instrumentelor si procedurilor medicale de ultima ora, utilizate eficient in interventiile preventive si curative.

Imbatranirea sanatoasa a devenit dezideratul suprem al politicilor internationale de sanatate si al comunitatii oamenilor de stiinta din intreaga lume. Din pacate bolile de memorie afecteaza majoritar populatia de peste 60 de ani, deci riscul pierderii definitive a calitatii vietii, prin handicap fizic si psihic este enorm, in conditiile in care in Romania aceste centre specializate sunt in faza de pionierat. Numai cel care o data in viata lui a vazut sau a ingrijit pe cineva poate intelege drama pacientului si a ingrijitorului, precum si inalta specializare a serviciilor de oferit acestor pacienti si familiilor lor.

PROTOCOALE DE MANAGEMENT

Formează profesional, începând cu anul 1996, peste 7,500 de studenți, rezidenți, specialiști în Neurologie, Psihiatrie, Medicină de Familie, Neuroimagistică, Medicină de Laborator (biomarkeri pentru îmbătrânirea patologică), asistenți medicali generaliști.

Elaborează primul Syllabus și Curricula în Geriatrie și Gerontologie academică în 1998, OBȚINÂND PENTRU PRIMA OARĂ recunoașterea academică a specialității de Geriatrie și Gerontologie.

Începând cu 2010 coordonează grupul de experți pentru elaborarea Curriculei și Syllabus-ului de Metode și tehnici în Brain Aging, în cadrul unui proiect strategic național de educație integrată pentru medici din 7 specialități și asistenți medicali.

Coordinating EU Funded Projects since 1996, for educational, for research and for sharing knowledge (networking and patient support) purposes

  1. Educational projects:

i) 1997-2001: Program Director and coordinator Tempus Phare ROMGER SJEP 12507, project created for the following objectives:

    1. obtain academical recognition of the Geriatrics-Gerontology specialty in Romania
    2. establish the first University College of Geriatrics, Gerontology and Social Assistance for Elders, within UMF “Carol Davila”;
    3. develop the first Curriculum and Syllabus in Geriatrics, Gerontology and Psychogeriatrics within a European consortium including Geriatric Clinical Departments in Sweden,France, Greece, Spain, Italy and Israel
    4. establish the first University Clinic of Geriatrics and Gerontology inside “Ana Aslan” Hospital, Otopeni, Romania.

ii) 2010-2012: Coordinator and Curriculum/Syllabus developer, BrainAging project [Professional Training on New Medical Technologies Related to Brain Aging, for the Specialized Medical and Nursing Staff] POSDRU/81/3.2/S/46975

2. RESEARCH PROJECTS 2018 -  Ongoing

i) 2018- 2021: PETAL project: AAL-2016 [Ambient Assistive Living: intelligent lights to be used for the cognitive delay MCI patients, independent seniors, at home or in residential houses, out/in patients for Memory Clinics]

ii) 2018-2022: IOANNA project: AAL-2017 [Integration Of All stores Network and Navigation Assistant]

iii) 2018- 2022: Ella4Life project: AAL-2017 [Virtual Assistant for Seniors]

iv) 2019: VirtuAAL project: AAL-2018 SCP [Virtual And Augmented Reality For Combating Cognitive Impairment]

v) 2019- 2022: FrAAgiLe project: AAL-2018 [Platform for detecting frailty and falls]

vi) 2019-2021: POSITIVE project: AAL-2018 [Personalized Platform assisting seniors in healthy fulfilled and active life]

vii) 2019-2023: SMART BEAR EC H2020 Project [Smart Big Data Platform to Offer Evidence-based Personalized Support for Healthy and Independent Living at Home] - coordonating the Romanian Pilot of 1,000 elderlies at home

viii) 2020-2022: iCan project: AAL-2019 [ICT-based assistant for everyday life]

ix) 2020-2023: ReMember-Me project: AAL-2019 [Smart assistant to prevent and detect cognitive decline, promote cognitive function and social inclusion among older adults]

3. Networking, sharing best practices and patient’s support projects

i) 2011 – 2013: funding member of the network, within Ageing Well project; CIP-ICT-PSP-2011-5 - Network for the Market uptake of ICT for Ageing Well

ii) 2012 – 2014: involved in the development, assessment and validation of the ICT platform for patients with Parkinson disease, developed by the LiveWell project; 527943-LLP-1-2012-1-PT- GRUNDTVIG-GMP [Promoting Healthy Living and Well-being for Parkinson Patients through Social Network and ICT Training]

iii) 2013 – 2015: involved in the development, assessment and validation of the ICT platform for elders, developed by the E-NO FALLS project; ICT Policy Support Programme, Call : CIP-ICT-PSP- 2012-6, [European Network fOr FALL Prevention, Intervention & Security]

iv) 2020-2024: COST Action CA 19121 (GoodBrother: Network on Privacy - Aware Audio- and Video-Based Applications for Active and AssistedLiving) member of the Management Committee for Romania and leader of WG 3 - Audio-and video-based AAL applications.

v) 2020-2024: COST Action CA 19136 (NET4AGE-FRIENDLY: International Interdisciplinary Network on Smart Healthy Age-friendly Environments) member of the Management Committee for Romania and leader of WG 4 - SHAFE impact and sustainability: policy development, funding forecast and cost benefit evaluations.

vi) 2019 – 2023: Principal Investigator and coordinator for in the european research project RADAR-AD (Remote Assessment of Disease and Relapse – Alzheimer’s Disease) within IMI 2 (Innovative Medicine Initiative), Grant Nr. 806999, financedfrom H2020 R&D and EFPIA programs

  • 2015  –  2018: Coordonator Centru pilot de evaluare si validare a platformelor de asistare ambientala inteligenta (AAL) si noua tehnologie utilizata in scopul acordarii de servicii medicale si de autoingrijire la domiciliua varstnicilor, elaborate in proiectul multinational SeniorTV AAL-Call-2014 [Providing ICT-based formal and informal care at home], UEFSCIDI, in cadrul programului de Cooperare al FP7, si respectiv Planului National de Cercetare, Dezvoltare si Inovare II
  • 2015 – 2017: Coordonator Centru pilot de evaluare si validare a platformelor de asistare ambientala inteligenta (AAL) si noua tehnologie utilizata in scopul acordarii suportului tehnico-medical necesar cadrelor medicale medii care se ocupa de ingrijirea varstnicilor, elaborate in proiectul multinational MyMate AAL-Call-2014 [Gamified Collaborative Platform for the Promotion of Sustainable Care and Independent Assisted Living], UEFSCIDI, in cadrul programului de Cooperare al FP7, si respectiv Planului National de Cercetare, Dezvoltare si Inovare II
  • 2014 – 2016: Coordonator Centru pilot de evaluare si validare a platformelor de asistare ambientala inteligenta (AAL) si noua tehnologie medicala pentru persoanele active care lucreaza intr-un mediu stresant, elaborate in proiectul multinational StayActive AAL-Call- 6, [Work with no stress about the stress] http://stay-active.net, UEFSCIDI, in cadrul programului de Cooperare al FP7, si respectiv Planului National de Cercetare, Dezvoltare si Inovare II
  • 2014 – 2016: Coordonator Centru pilot de evaluare si validare a platformelor de asistare ambientala inteligenta (AAL) pentru educarea, acordarea de suport tehnico-medical si socializarea persoanelor care se ocupa de ingrijirea de lunga durata a pacientilor cu nevoi speciale de ordin fizic si cognitiv, elaborate in proiectul multinational CarerSupport AAL-Call-5, [Integrated Platform for Informal Carer’s Training, Tele-consulting and Collaboration]

http://www.itfunk.org/docs/prosjekter/AAL-CarerSupport.htm, UEFSCIDI, in cadrul programului de Cooperare al FP7, si respectiv Planului National de Cercetare, Dezvoltare si Inovare II

  1. Geriatrie-Tratat, Luiza Spiru, Ioan Romosan, Editura ,,Ana Aslan International Academy of Aging, Bucuresti”, 2004
  2. Interdisciplinaritatea bolilor renale si digestive, Luiza Spiru, Ioan Romosan, Ana Aslan International Academy of Aging, 2004
  3. Managementul bolilor de memorie – Ghid practic, 2006, Luiza Spiru – ISBN 973 -8611-4-4-2006
  4. .Scale specifice de evaluare si diagnostic de specialitate,  traduse si adaptate in limba romana, Luiza Spiru; Brain Aging International Journal – editie in limba romana, ISSN 1582-8360: Testul MMSE (Mini Mental State Examination), Testul OROLOGIULUI,Scorul activitãtilor vietii cotidiene (ADL), Scorul IADL al activitãtilor curente, SIB (Severe Impairment Batery), NPI (Neuropsychiatric Inventory), ZARIT : Evaluarea sarcinii ajutorului principal, Scorul riscului vascular HACKINSKY, Evaluarea echilibrului static si dinamic in timpul mersului: Proba Tinetti, Test de fluenta verbala, Clinical Global Impression (CGI).
  5. FOILE DE OBSERVATIE SPECIFICE PACIENTILOR GERIATRICI
  • Fisa de Consultatie Ambulatorie, Luiza Spiru, Editura „Ana Aslan” International Academy of Aging, Bucuresti
  • Foaia de Observatie Geriatrica – Baza Clinica Olanesti, Luiza Spiru, Editura „Ana Aslan” International Academy of Aging, Bucuresti
  • Foaie de Observatie Geriatrica – Ambulatoriu de Specialitate, Luiza Spiru, Editura „Ana Aslan” International Academy of Aging, Bucuresti, 2008
  1. Actual coordinates of the research on aging in Romania, Luiza Spiru, Ileana Turcu: The International Handbook on Aging, Third Edition, EB. Palmore, F Whittington, SR. Kunkel eds., Praeger Publishers, Connecticut, SUA, 2009
  2. ,,TRATAT DE GERIATRIE  – o abordare integata, predictiva si personalizata”,initiat in ianuarie 2010 sub coordonarea Conf. Dr. Luiza Spiru – in curs de editare, cu participarea a peste 30 de specialisti romani.
  3. Ghid de practică medicală pentru specialitatea Geriatrie Gerontologie si anexele sale, Evaluarea geriatrica si Foaia de consult geriatric, aprobate prin Ordinul ministrului sanatatii Nr. 1454/30.11.2010
  4. Curricula de pregatire in rezidentiat, specialitatea Geriatrie Gerontologie, Conform adresei Nr. VIIId/47526/16.08.2010, inaintata de Directia Generala Resurse Umane si Certificare a Ministerului Sanatatii
  5. Curriculum si Syllabus de Medicina Geriatrica-Gerontologica si Psihogeriatrie pentru Specialitatea Medicina de Familie, Conform Decizie Comisia Nationala de Geriatrie Gerontologie a MS, 2011
  6. Ghid de bună practică în Ingrijirea la domiciliu şi Case Rezidențiale, Conform Decizie Comisia Nationala de Geriatrie Gerontologie a MS, 2011
  7. "LiveWell – Promoting Healthy Living and Wellbeing for Parkinson Patients through Social Network and ICT Training: Lessons Learnt and Best Practices"; Maged N. Kamel Boulos (University of the Highlands and Islands, UK), Emmanuel Ifeachor (Plymouth University, UK), Javier Escudero (Edinburgh University, UK), Peng Zhao (Plymouth University, UK), Camille Carroll (Plymouth University, UK), Pedro Costa (INOVAMAIS – Serviços de Consultadoria em Inovação Tecnológica, S.A., Portugal), Gerhard Doppler (Bit media e-solutions GmbH, Austria), Laura Carrasco Marín (Asociacíon Parkinson Madrid, Spain), Luiza Spiru (Ana Aslan International Foundation, Romania), Kristin Helga Guðmundsdótti (Samvil ehf. Fjarkennsla.com, Iceland) and Marija Kosem (Splošna bolnišnica Brežice, Slovenia); Health Literacy: Breakthroughs in Research and Practice, Chapter: 21; Publisher: IGI Global, Hershey, Pennsylvania (USA); Editors: Information Resources Management Association USA; ISBN: 978-1522519287, DOI: 10.4018/978-1-5225-1928-7.ch021; November 2017
  8. "Medicina Longevitatii - TRATAT DE GERIATRIE”, Prof.Dr. Luiza Spiru, Acad. Prof.Dr. Ioan Romosan, Editura "Ana Aslan International Academy of Aging, Bucuresti”, 2018, ISBN 978-973-86411-6-7
  9. "AETERNUS: Tratat de Geriatrie și Medicina Longevității", coordonatori Prof. Luiza Spiru și Prof Ioan Romosan, cu contribuția a peste 30 de specialiști români - 2020, Ed. Academiei Romane, ISBN 978-973-27-3203-8
  1. LS - MCI patients in Europe: Medication and comorbidities.The DESCRIPA study,TskolakiM,PapaliagkasV,FrisoniG,JonesR,TouchonJ, Spiru L, Vellas B, Verhey F, Visser P, Winblad B, Current Alzheimer Research, vol.13 , issue 12 (2016)
  2. Impact of biomarkers on diagnostic confidence in clinical assessment of patients with suspected Alzheimer's Disease and high diagnostic uncertainty: an EADC Study, Paolo Bosco, Alberto Redolfi, Martina Bocchetta, Clarissa Ferrari, Anna Mega, Samantha Galluzzi, Frederic Assal, Mircea Balasa, Christine Bastin, Anastasia Bougea, Derya Durusu Emek-Savas, Sebastiaan Engelborghs, Panteleimon Giannakopoulos, Gabriel Gold, Timo Grimmer, Galina Grosu, Milica G. Kramberger, Brian Lawlor, Gorana Mandic Stojmenovic, Mihaela Marinescu, Patrizia Mecocci, Jose Luis Molinuev, Ricardo Morais, Ellis Niemantsverdriet, Flavio Nobili, Konstantinos Ntovas, Sarah O’Dwyer, George Paraskevas, Luca Pelini, Agnese Picco, Eric Salmon, Isabel Santana, Oscar Sotolongo-Grau, Luiza Spiru, Elka Stefanova, Katarina Surlan Popovic, MagdaTsolaki,Gorsev Yener, Dina Zekry, Giovanni B. Frisoni; Alzheimer's & Dementia: the journal of the Alzheimer's Association Volume 12, Issue 7, Supplement, Pages P904–P905, July 2016; DOI: https://doi.org/10.1016/j.jalz.2016.06.1871
  3. The impact of automated hippocampal volumetry on diagnostic confidence in patients with suspected Alzheimer'sdisease:AnEADC study,Paolo Bosco, Alberto Redolfi, Martina Bocchetta, Clarissa Ferrari, Anna Mega, Samantha Galluzzi, Mark Austin, Andrea Chincarini, Louis Collins, Simon Duchesne,Benedicte Marechal, Alexis Roche, Francesco Sensi, Robin Wolz, Montserrat Alegret, Frederic Assal, Mircea Balasa, Christine Bastin, Anastasia M Bougea, Derya Durusu Emek-Savas,Sebastiaan Engelborghs, Timo Grimmer, Galina Grosu, Milica Kramberger, Brian A Lawlor, Gorana Mandic, Mihaela Marinescu, Patrizia Mecocci, Jose Luis Molinuevo, Ricardo Felix-Morais, Ellis Niemantsverdriet, Flavio Nobili, Konstantinos Ntovas, Sarah O’Dwyer, George P. Paraskevas, Luca Pelini, Agnese Picco, Eric Salmon, Isabel Santana, Oscar Sotolongo-Grau, Luiza Spiru, Elka Stefanova, Katrina Surlan Popovic, Magdalini Tsolaki, Gorsev G Yener, Dina Zekry, Giovanni B. Frisoni, Alzheimer's &Dementia: the journal of the Alzheimer's Association · March2017.
  4. Genetic Risk as a Marker of Amyloid-β and Tau Burden in Cerebrospinal Fluid, Voyle N, Patel H, Folarin A, Newhouse S, Johnston C, Dobson R, Kiddle S, Visser P, Tsolaki M, Wahlund L, Yvonne-Freund-Levi, Verhey F, Hausner L, Johannsen G, Teunissen C, Vandenberghe R, Spiru L, Wallin A, Olde-Rikkert M, Journal of Alzheimer’s Disease, vol.55, Issue 4(2017)
  5. Association between Later Life Lifestyle Factors and Alzheimer's Disease Biomarkers in Non-Demented Individuals: A Longitudinal Descriptive Cohort Study, Reijs B, Vos S, Soininen H, Lötjonen J, Koikkalainen J, Pikkarainen M, Hall A, Vanninen R, Liu Y, Herukka S, Freund-Levi Y, Frisoni G, Frölich L, Nobili F, Rikkert M, Spiru L, Tsolaki M, Wallin Å, Scheltens P, Verhey F, Visser P, Journal of Alzheimer's Disease (2017) 60(4) 1387-1395
  6. Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia, Willemijn J. Jansen, PhD; Rik Ossenkoppele, PhD; Betty M. Tijms, PhD; Anne M. Fagan, PhD; Oskar Hansson, MD, PhD; William E. Klunk, MD, PhD; Wiesje M. van der Flier, PhD; Victor L. Villemagne, MD, PhD; Giovanni B. Frisoni, MD; Adam S. Fleisher, MD, MAS; Alberto Lleó, MD, PhD; Mark A. Mintun, MD; Anders Wallin, MD, PhD; Sebastiaan Engelborghs, MD, PhD; Duk L. Na, MD, PhD; Gäel Chételat, PhD; José Luis Molinuevo, MD, PhD; Susan M. Landau, PhD; Niklas Mattsson, MD, PhD; Johannes Kornhuber, MD; Osama Sabri, MD, PhD; Christopher C. Rowe, MD, PhD; Lucilla Parnetti, MD, PhD; Julius Popp, MD; Tormod Fladby, MD, PhD; William J. Jagust, MD, PhD; Pauline Aalten, PhD; Dong Young Lee, MD, PhD; Rik Vandenberghe, MD, PhD; Catarina Resende de Oliveira, MD, PhD; Elisabeth Kapaki, MD, PhD; Lutz Froelich, MD, PhD; Adrian Ivanoiu, MD, PhD; Tomasz Gabryelewicz, MD, PhD; Marcel M. Verbeek, PhD; Páscual Sanchez-Juan, MD, PhD; Helmut Hildebrandt, PhD; Vincent Camus, MD, PhD; Marzena Zboch, MD, PhD; David J. Brooks, MD, PhD; Alexander Drzezga, MD, PhD; Juha O. Rinne, MD, PhD; Andrew Newberg, MD, PhD; Alexandre de Mendonça, MD, PhD; Marie Sarazin, MD, PhD; Gil D. Rabinovici, MD; Karine Madsen, MD, PhD; Milica G. Kramberger, MD, PhD; Agneta Nordberg, MD, PhD; Vincent Mok, MD; Barbara Mroczko, MD; David A. Wolk, MD; Philipp T. Meyer, MD, PhD; Magda Tsolaki, MD, PhD; Luiza Spiru MD, PhD; Amyloid Biomarker Study Group; Philip Scheltens, MD, PhD; Frans R. J. Verhey, MD, PhD; Pieter Jelle Visser, MD, PhD; November 2017, JAMA Psychiatry 75(1), DOI: 10.1001/jamapsychiatry.2017.3391
  7. Prevalence of the Apolipoprotein E ε4 allele in amyloid-β positive subjects across the spectrum of Alzheimer’s disease, Niklas Mattsson*, MD, PhD; Colin Groot, MSc; Willemijn J. Jansen, PhD; Susan Landau, PhD; Victor Villemagne, MD, PhD; Sebastiaan Engelborghs, MD, PhD;Mark Mintun, MD; Alberto Lleo, MD, PhD; José Luis Molinuevo, MD, PhD;William Jagust, MD; Giovanni B. Frisoni, MD; Adrian Ivanoiu, MD, PhD; GaëlChételat, PhD; Catarina Resende de Oliveira, MD, PhD; Karen M. Rodrigue, PhD;Johannes Kornhuber, MD; Anders Wallin, MD, PhD; Aleksandra Klimkowicz-Mrowiec, MD, PhD; Ramesh Kandimella, PhD; Julius Popp, MD; Pauline P Aalten,PhD; Dag Aarsland, MD, PhD; Daniel Alcolea, MD, PhD; Ina S. Almdahl, MD; InêsBaldeiras, PhD; Mark A. van Buchem, MD, PhD; Enrica Cavedo, PhD; Kewei Chen,PhD; Ann D. Cohen, PhD; Stefan Förster, MD, PhD; Juan Fortea, MD, PhD; KristianS. Frederiksen, MD, PhD; Yvonne Freund-Levi, MD, PhD; Kiran Dip Gill, PhD;Olymbia Gkatzima, MSc; Timo Grimmer, MD, PhD; Harald Hampel, MD, PhD;Sanna-Kaisa Herukka, PhD; Peter Johannsen, MD, PhD; Koen van Laere, MD, PhD,DrSc; Mony de Leon, MD, PhD; Wolfgang Maier, MD, PhD; Jan Marcusson, MD,PhD; Olga Meulenbroek, PhD; Hanne M. Møllergård, PhD; John C. Morris, MD,PhD; Barbara Mroczko, MD, PhD; Arto Nordlund, PhD; Sudesh Prabhakar, MD,PhD; Oliver Peters, MD; Lorena Rami, MSc; Eloy Rodríguez-Rodríguez, MD, PhD;Catherine M. Roe, PhD; Eckart Rüther, MD, PhD; Isabel Santana, MD, PhD;Johannes Schröder, MD, PhD; Sang W. Seo, MD, PhD; Hilkka Soininen, MD, PhD;Luiza Spiru, MD, PhD; Erik Stomrud, MD, PhD; Hanne Struyfs, MSc; Charlotte E.Teunissen, PhD; Frans RJ Verhey, MD, PhD; Stephanie J.B. Vos, PhD; Linda J.C.van Waalwijk van Doorn, MSc; Gunhild Waldemar, MD, DMsc; Åsa K. Wallin, MD,PhD; Jens Wiltfang, MD, PhD; Rik Vandenberghe, MD, PhD; David J. Brooks, MD,PhD; Tormod Fladby, MD, PhD; Christopher C. Rowe, MD, PhD; AlexanderDrzezga, MD, PhD; Marcel M. Verbeek, PhD; Marie Sarazin, MD, PhD; David A.Wolk, MD; Adam S. Fleisher, MD, MAS; William E. Klunk, MD, PhD; Duk L. Na,MD, PhD; Pascual Sánchez-Juan, MD, PhD; Dong Young Lee, MD, PhD; AgnetaNordberg, MD, PhD; Magda Tsolaki, MD, PhD; Vincent Camus, MD, PhD; Juha O.Rinne, MD, PhD; Anne M. Fagan, PhD; Henrik Zetterberg, MD, PhD; Kaj Blennow,MD, PhD; Gil D. Rabinovici, MD; Oskar Hansson, MD, PhD; Bart N.M. van Berckel,MD, PhD; Wiesje M. van der Flier, PhD; Philip Scheltens, MD, PhD; Pieter JelleVisser, MD, PhD; & Rik Ossenkoppele*, PhD., Alzheimers' and Dementia Volume 14, Issue 7, Pages 913–924, July 2018;DOI: https://doi.org/10.1016/j.jalz.2018.02.009
  8. Duration of preclinical, prodromal, and dementia stages of Alzheimer’s disease in relation to age, sex, and APOE genotype, Lisa Vermunta, Sietske A. M. Sikkes, Ardo van den Hout, Ron Handels, Isabelle Bos, Wiesje M. van der Flier, Silke Kern, Pierre-Jean Ousset, Paul Maruff, Ingmar Skoog, Frans R. J. Verhey, Yvonne Freund-Levi, Magda Tsolaki, Asa K. Wallin, Marcel Olde Rikkert, Hilkka Soininen, Luisa Spiru, Henrik Zetterberg, Kaj Blennow, Philip Scheltensa, Graciela Muniz-Terrera, Pieter Jelle Visser, for the Alzheimer Disease Neuroimaging Initiative, AIBL Research Group, ICTUS/DSA study groups; Alzheimers' and Dementia Volume 15, Issue 7, Pages 888–898, July 2019; DOI: https://doi.org/10.1016/j.jalz.2019.04.001
  9. Biomarker-based prognosis for people with mild cognitive impairment (ABIDE): a modelling study, Ingrid S van Maurik, Stephanie J Vos, Isabelle Bos, Femke H Bouwman, Charlotte E Teunissen, Philip Scheltens, Frederik Barkhof, Lutz Frolich, Johannes Kornhuber, Jens Wiltfang, Wolfgang Maier, Oliver Peters, Eckart Rüther, Flavio Nobili, Giovanni B Frisoni, Luiza Spiru, Yvonne Freund-Levi, Asa K Wallin, Harald Hampel, Hilkka Soininen, Magda Tsolaki, Frans Verhey, Iwona Kłoszewska, Patrizia Mecocci, Bruno Vellas, Simon Lovestone, Samantha Galluzzi, Sanna-Kaisa Herukka, Isabel Santana, Ines Baldeiras, Alexandre de Mendonça, Dina Silva, Gael Chetelat, Stephanie Egret, Sebastian Palmqvist, Oskar Hansson, Pieter Jelle Visser, Johannes Berkhof, Wiesje M van der Flier, for the Alzheimer’s Disease Neuroimaging Initiative; The Lancet Neurology Vol 18, Issue 11, Pages 1034-1044, Nov 01, 2019; DOI: https://doi.org/10.1016/S1474-4422(19)30283-2
  10. Biomarker counseling, disclosure of diagnosis and follow‐up in patients with mild cognitive impairment: A European Alzheimer's disease consortium survey, Frederiksen, K.S., Nielsen, T.R., Appollonio, I., Andersen, B.B., Riverol, M., Boada, M., Ceccaldi, M., Dubois, B., Engelborghs, S., Frölich, L., Hausner, L., Gabelle, A., Gabryelewicz, T., Grimmer, T., Hanseeuw, B., Hort, J., Hugon, J., Jelic, V., Koivisto, A., Kramberger, M.G., Lebouvier, T., Lleó, A., de Mendonça, A., Nobili, F., Ousset, P.‐J., Perneczky, R., Olde Rikkert, M., Robinson, D., Rouaud, O., Sánchez, E., Santana, I., Scarmeas, N., Sheardova, K., Sloan, S., Spiru, L., Stefanova, E., Traykov, L., Yener, G. and Waldemar, G. (2021), Int J Geriatr Psychiatry, 36: 324-333; September 2020;https://doi.org/10.1002/gps.5427
  11. Pre‐fall prognostics, prevention and management of frailty in geriatrics: A personalized intelligent system approach (ALL‐FrAAgile), Marinescu, M., Bartolome, I., Marzan, M., Mashayekhi, K. and Spiru, L.; Alzheimer's & Dementia, Volume 16, Issue S8: e043449, December 2020;https://doi.org/10.1002/alz.043449
  12. Biomarker counseling, disclosure of diagnosis, and follow‐up in patients with mild cognitive impairment: A European survey of EADC centers, Frederiksen, K.S., Nielsen, R., Robinson, D., Hausner, L., Hanseeuw, B.J., Nobili, F.M., Rikkert, M.G.O., Hugon, J., Andersen, B.B., Mendonca, A., Traykov, L., Yener, G., Scarmeas, N., Sloan, S., Gabryelewicz, T., Ousset, P.J., Hort, J., Rouaud, O., Gabelle, A., Sheardova, K., Engelborghs, S., Dubois, B., Grimmer, T., Apollonio, I., Perneczky, R., Spiru, L., Koivisto, A.M., Santana, I., Ceccaldi, M. and Waldemar, G. (2020); Alzheimer's & Dementia, Volume 16, Issue S8: e039026, December 2020; https://doi.org/10.1002/alz.039026

U.M.F. "Carol Davila" din București

Adresa:
Strada Dionisie Lupu nr. 37, Sector 2, București. Cod poștal: 020021

Cod fiscal: 4192910

Telefon:
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+4021 3180721
+4021 3180722
E-mail: rectorat@umfcd.ro

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